But Pakistan reached the target in 35.5 overs for the loss of just five wickets, with Mohammad Fayyaz hitting 101 - his second century of the series. Fayyaz hit eleven boundaries and was ably assisted by Mohammad Waqas (62) and Mohammad Shahbaz, who made 46.
Pakistan won the first two matches in Lahore and Karachi, while India came back to win the third match, also held in southern port city of Karachi.
The final match of the series will be played in the garrison city of Rawalpindi, next to the capital Islamabad, on Sunday.
India's blind cricket team is on its maiden foreign tour and is also playing a series against arch-rival Pakistan for the first time.
Indian blind cricketers crush Pak