The Multan-born Inzamam scored hundreds in both previous Tests played at the plush cricket stadium on the outskirts of his home town against Bangladesh in 2001 and 2003.
The 34-year-old knows he needs to make another tall score against the Indians if Pakistan are to win the first Test and take the lead in the three-match series.
"It is always a special motivation while playing before my own people and this is a very special occasion," said the Pakistan captain, the son of a renowned cleric in Multan.
"Probably the pressure is a bit more because the people expect a lot from me, but that will always keep me on my toes. "I will be very happy if I can get runs and inspire my team to win."
The solid middle order batsman is the mainstay of Pakistan's line-up after scoring 6,680 runs from 91 Tests with 18 centuries.
Inzamam hopes to put aside the disappointment of the 3-2 defeat in the One-day series against the tourists and wants his team to make a fresh start in the Test matches. "India may have gained the edge by winning the One-dayers, but I am confident we can regroup and stage a comeback in the Tests," he said.
Inzamam hit centuries in the first match at Karachi and the fourth in Lahore, but Pakistan lost both games as India drew level 2-2 and then won the decider on Wednesday.
"My two Test hundreds in Multan against Bangladesh helped Pakistan win both times and I hope the same will be repeated against India," he said. "The wicket is usually very sporting, helping both the bowlers and the batsmen. It should be a great start to the Test series."
The second Test will be played in Lahore from April 5-9 and the third in Rawalpindi from April 13-17.