Dhoni smashed the ball around to hit 13 fours and a six in his 68-ball blitz.
Rohan Gavaskar (unbeten 89 off 79 balls with 9 fours and a six) and Laxmi Ratan Shukla (60 in 58 balls with 6 fours) chipped in nicely as East successfully overhauled Central's tall score with an over to spare by making 348 for six.
Earlier, Central's Suresh Raina and Abbas Ali cracked centuries after skipper Mohd Kaif won the toss and chose to bat first and guided their side to an imposing 346 for 8 in 50 overs.
The two batsmen rescued Central after they lost three wickets, including that of Kaif (14), within the first ten overs with a double century stand for the fourth wicket which was worth exactly 200 runs and in 179 balls.
Rana struck four sixes and 14 fours in his 104-ball 129, while Ali made 100 off 103 balls with 12 fours and one six. J P Yadav (43) and Jyoti Yadav (22) provided useful contributions in the end.
Sanjib Sanyal of Bengal was East's most successful bowler with a four-wicket haul.
East Zone, who had minus 2 points in their kitty before the match, secured four points to take their overall points to plus 2 at the end of their league engagements.