"Tendulkar's stars show his career will end this year and the latest operation may prove to be the cause," Lahore-based Abdullah Shaukat Chowdhry has been quoted as saying by a British website.
It may be recalled that the 32-year-old Sachin had undergone an operation for tennis elbow in London last week which has ruled him out of action for atleast four months.
One of the premier batsman in the game's annals and a former India captain, Sachin has scored 10,134 runs in Tests and a world record 13,642 runs in One-day Internationals.
But his career has been threatened by a spate of injuries over the last years - back, toe and now elbow.
"I use astrology charts and as per the position of the stars on the charts, a prediction is made. Tendulkar's date of birth suggests positions of Jupiter and Mars are not good," said 70-year-old Chowdhry, a cricket fan said.
"I wish I am wrong but this is what stars tell," he said.
Tendulkar's elbow injury first surfaced in Holland last year when India went there to play in a One-day tri series with Pakistan and Australia.
It forced him to miss that tri-series, the three-match NatWest Challenge with England that followed, the Champions Trophy played in England and two home Tests against Australia late last year.
"Cricket is my area of interest and any cricketer needing fair help is welcome," said Chowdhry whose famous predictions include former Pakistan great Imran Khan to suffer a shin bone injury in 1980s, Pope John Paul to die because of ill health in 2005, an earthquake to hit South Asia in December 2004 and Tony Blair to win a third election.
"I used to predict a lot on the outcome of cricket matches but after some of the predictions went wrong, mainly because of match fixing, I now refuse to predict on cricket matches," said Chowdhry, who correctly predicted India's 2-1 win in the Test series in Pakistan last year.