Set up in 2001, the lecture honours the memory of the late Colin Cowdrey, the outstanding Kent and England batsman, whom Boycott played alongside during the 1960s and 1970s.
As well as his artistry with the bat Cowdrey, also an England captain, was well-known for his sportsmanship.
And one of Cowdrey's major contributions to the game after his retirement as a player was as the main driving force behind the insertion of the 'Spirit of Cricket' preamble into the 2000 code of the sport's Laws, still the responsibility of Lord's owners Marylebone Cricket Club (MCC).
Boycott, 64, was one of England's most outstanding opening batsman and was especially renowned for his impressive defence.
He helped cement his place in the history of cricket in 1977 when he became the first man to score his 100th first-class century in a Test match, reaching three figures on his Headingley home ground against Australia.
Boycott, who recently returned to comentating after a bout of throat cancer, will be the first Englishman to give the Cowdrey Lecture, at Lord's on July 19, since it was inaugurated in 2001.
He follows former Australian captain and fellow broadcaster Richie Benaud and three playing contemporaries in South Africa's Barry Richards and Sunil Gavaskar, two other leading opening batsmen during the 1970s, as well as another opponent in former West Indies captain Clive Lloyd.