Vaughan has not played since being forced home from the tour of India in February by a persistent knee problem.
But there had been reports suggesting that having resumed training with Yorkshire, he would play in the County Championship clash with Kent at Canterbury starting on Wednesday.
Not so, said Yorkshire's director of cricket David Byas.
"Michael won't be playing. There has been talk of him coming back this week but that's absolute eye-wash," Byas said.
"Quite when he's going to be back, I'm not sure - I can only say he's making progress."
There is a possibility Vaughan could make his comeback in the championship match against Lancashire next week and return to the international fold when the second Test gets under way on May 25.
But Byas insists Vaughan will not be compelled to rush back into action.
"If he comes back sooner than he should then it would a waste of time," Byas added.
"He's very keen to come back, but come back when he's ready.
"He's worked very hard to get where he is - he's the captain of England - and he's a mature, professional cricketer, so he's not going to throw that away.