Ntini, who also won the Proteas Test Cricketer of the Year accolade, was given the award in a glittering ceremony as he capped a second successful season with a haul of 48 wickets.
Pollock was presented the South African One-day Cricketer of the year award and also emerged as his teammates choice for the Player of the Year award.
Young star AB de Villiers, who has been playing multiple roles of a reserve wicketkeeper and opening batsman, was the fans' favourite and he gobbled the most number of votes to win the popular award.
The best Newcomer award went to talented allrounder Johan Van der Wath.
In total, 30 awards were presented at a ceremony attended by leading sporting and business dignitaries. Apart from the national players, domestic cricketers and local officials were also honoured at the ceremony.
The awardees: Cricketer of the Year: Makhaya Ntini ODI Cricketer of the Year: Shaun Pollock Test Cricketer of the Year: Makhaya Ntini Newcomer of the Year: Johan van der Wath Fans' Cricketer of the Year: AB de Villiers Players' Player of the Year: Shaun Pollock