Smarting from a 1-4 defeat in England's tour of India last year, which also included a match in Kolkata, the sprightly pacer told BBC Sports that she was eager to settle the score this time.
''I am looking forward to gaining revenge on the Indians and offer some sort of experience to the newer players,'' Isa told BBC Sports.
And she would leave no stone unturned in her efforts to chip in with both the ball and the bat, asserted Isa.
''I tend to seam the ball rather than swing it and my aim will be to put pressure on the batsmen forcing to play a game that is not natural to them.
''I have worked a lot on my batting and hopefully produce valuable runs lower down the order. I am hoping to retain my place in the field as square leg specialist,'' she said.
Indian eves kick off the tour with a NatWest International Twenty20 Cup match at Derbyshire on Saturday, followed by the first Test which begins at Leicestershire on August 8, while the second Test starts from August 29.
In between, they play the ODIs on August 14 ((Lord's), August 17 (Shenley), August 19 (Arundel), August 24 and 25 (Hampshire Rose Bowl).
Isa also pledged support for new captain Charlotte Edwards.
''Lottie has officially taken over the captaincy since Clare Connor retired early on in the year. Up until now she has been the most prolific run scorer in the women's game and bowls anything from spin to seam! She has all-round cricketing knowledge and the team will be fully behind her,'' she said.
Newly appointed vice captain Laura Newton would also provide valuable support to ''Lottie'', she said.
''She (Newton) has enforced her place as an opening bat and on her day can rip bowling attacks apart. In the meantime she has been working on her off spin so don't be surprised to see her turning her arm over.
''She is also one player that I admire as she is the only one with two children to look after as well as juggling a part-time degree and training,'' Isa added.
She singled out Rosalie Birch from the present squad and said, '''Cheesy' is a player that has the ability to make something happen whether it's with the bat or the ball.
''She tends to have a knack of picking up wickets when required.
She also bats in the middle order and is a very attacking bat who is capable of scoring big runs. She has recently used her cricket talents to travel to India in order to raise money for Sport Relief,'' Isa explained.
She also expected some good shows from her Reading and Berkshire team-mate Claire Taylor.
''She has a lot of experience behind her and always seems to come up trumps with the bat. She is another hard-hitting batsman who looks busy in the crease and can be slightly unorthodox which makes her hard to bowl against.
''She is probably one of our more logical thinkers having studied maths at Oxford,'' she quipped.