England were unchanged from the team that won the third Test at Headingley by 167 runs, where they took an unbeatable 2-0 lead in the four-match series, with Jon Lewis again dropping out from the 12-man squad.
Pakistan made three changes with Mohammad Hafeez, playing his first match of the series after his recent call-up, and Imran Farhat, fit again after a finger injury, replacing dropped opening batsmen Salman Butt and Taufeeq Umar - who've both left the tour.
And fast bowler Mohammad Asif, who hasn't featured in the series so far because of an elbow injury, replaced the out-of-form Mohammad Sami.
Hafeez hadn't played Test cricket since September 2003, when he made the last of his three apperances against Bangladesh.
England's Test series win was their first at home against Pakistan since 1982 and their first in Test cricket anywhere since last year's Ashes success against Australia.
England: Marcus Trescothick, Andrew Strauss (capt), Alastair Cook, Kevin Pietersen, Paul Collingwood, Ian Bell, Chris Read (wkt), Sajid Mahmood, Matthew Hoggard, Stephen Harmison, Monty Panesar
Pakistan: Mohammad Hafeez, Imran Farhat, Younis Khan, Mohammad Yousuf, Inzamam-ul-Haq (capt), Faisal Iqbal, Kamran Akmal (wkt), Shahid Nazir, Mohammad Asif, Umar Gul, Danish Kaneria
Umpires: Billy Doctrove (WIS), Darrell Hair (AUS)
TV umpire: Peter Hartley (ENUmG)
Match referee: Mike Procter (RSA)