Winning the toss and electing to bat, India made 239 for nine in the stipulated 50 overs with Amita Sharma returning unbeaten on 45.
In reply, Pakistan could only score 159 for six in full 50 overs.
Bismah Mahroof (43), Urooz Mumtaz (23) and Sajda Shah (44) were their main scorers.
Trish Kamni took three for 19 for India.
Earlier, India made a shaky start losing four wickets for only 51 runs as the two Pakistan medium pacers - Q Jalil and A Iqbal - shared the four wickets with the new ball.
Later, Kala and Dhar batted sensibly and put on 105 for the fifth wicket before the former departed. Kala made 45 with the help of six fours.
Dhar was out for 53 which was studded with four fours and a six, but Amita delighted with her solid unbeaten 45 in only 47 balls that contained six hits to the fence.
Jalil was the most successful Pakistani bowler, taking five for 62.
India 239 for 9 in 50 overs (Rumeli Dhar 53, Hemalat Kala 45, Amita Sharam 45 n o; Qanita Jalil 5 for 62, Asamvia Iqbal 2 for 47) beat Pakistan 159 for 6 in 50 overs (Sajda Shah 44, Taskeen 43, Urooz Mumtaz 23; Trish Kamini 3 for 19, Reema Malhotra 1 for 20)