Inzamam returned to the squad after missing the fourth match at Multan due to finger injury. Mohammad Yousuf, Umar Gul and Abdul Rehman also rejoined the team.
Yousuf missed the last match to attend to his pregnant wife, while Gul and Rehman were rested.
Shahid Afridi, Faisal Iqbal, Imran Farhat and Rao Iftikhar were left out.
The tourists made only one change from their line-up which won the fourth match at Multan by seven wickets as paceman Corey Collymore replaced Ian Bradshaw.
Pakistan leads the series 2-1 with first one-dayer cancelled due to rain.
Pakistan: Inzamam-ul-Haq (capt), Mohammad Hafeez, Yasir Hameed, Shoaib Malik, Mohammad Yousuf, Abdul Razzaq, Kamran Akmal, Rana Naved-ul-Hasan, Mohammad Sami, Abdul Rehman and Umar Gul
West Indies: Brian Lara (capt), Chris Gayle, Lendl Simmons, Shivnarine Chanderpaul, Marlon Samuels, Runako Morton, Dwayne Smith, Denesh Ramdin, Daren Powell, Dave Mohammed and Corey Collymore
Umpires: Nigel Llong (Eng), Asad Rauf (Pak) and Television umpire: Riazuddin (Pak)
Match referee: Alan Hurst (Aus)