England were unchanged from the side that won the second Test by an innings and 283 runs at Headingley, West Indies' heaviest Test innings defeat.
West Indies, now 1-0 down in the four-match series, made three changes.
Senior batsman Shivnarine Chanderpaul, who missed the Headingley match with a knee injury, returned in place of injured captain Ramnaresh Sarwan.
Batting all-rounder Darren Sammy became the first St Lucian to play Test cricket for the West Indies, effectively replacing Sylvester Joseph.
And fast bowler Fidel Edwards was recalled in place of Daren Powell.
Trinidad skipper Daren Ganga, previously the vice-captain, was captaining the West Indies in a Test for the first time after Sarwan sustained a tour-ending shoulder injury fielding at Headingley.
England: Andrew Strauss, Alastair Cook, Michael Vaughan (capt), Kevin Pietersen, Paul Collingwood, Ian Bell, Matthew Prior (wk), Liam Plunkett, Stephen Harmison, Ryan Sidebottom and Monty Panesar
West Indies: Chris Gayle, Daren Ganga (capt), Devon Smith, Runako Morton, Shivnarine Chanderpaul, Dwayne Bravo, Denesh Ramdin (wk), Darren Sammy, Jerome Taylor, Fidel Edwards and Corey Collymore
Umpires: Billy Bowden (NZ), Aleem Dar (Pak) and Third umpire: Peter Hartley (Eng)
Match referee: Alan Hurst (Aus).