Philander marked his 22nd birthday with four wickets for 12 runs in under six overs as Ireland were dismissed for 131 in a match reduced by rain to 31 overs per side.
His figures were the second best by a South African on one-day international debut after fast bowling great Allan Donald's five for 29 against India at Calcutta in 1991/92.
This was South Africa's first fixture since their seven-wicket World Cup semi-final defeat against eventual champions Australia in April and, looking to the future, they also gave a debut to off-spinner Thandi Tshabalala.
But it was Philander who caught the eye and, with a rested Pollock not selected, the Cape Cobras player will look to feature in South Africa's three-match one-day series against India starting at Stormont on Tuesday.
"He's done well back home in domestic cricket and that's the reason he got a call-up here," said Kallis, himself one of the world's leading all-rounders.
"He's a good all-rounder, someone we are going to try to mould along the lines of Shaun Pollock.
"They are big boots to fill, but he started well today (Sunday)," added Kallis, captaining South Africa in Ireland while regular skipper Graeme Smith recovers from knee surgery back home.
"He landed the ball in the right area, there was a little bit in the wicket and he exploited it expertly. I certainly hope he has a bright future ahead of him. He's had a good start."
Pollock, 33, has become one of the mainstays of the South Africa side since the team's re-admission to world cricket following the end of the apartheid era over a decade ago.
His accurate pace bowling has led to over 400 Test wickets and nearly that many in the one-day international arena although he hasn't scored the runs his batting ability would suggest.
However, Pollock's age appeared to be catching up with him at the World Cup where his declining pace was exploited by Australia opener Matthew Hayden in the semi-final after his accuracy against England had been vital in booking the Proteas' last four spot.
Philander bowled at a lively pace on Sunday. But a rain-freshened pitch assisted the quicks and Philander is likely to face sterner challenges than bowling against what is still effectively an amateur side.
Morne van Wyk's 52, his maiden one-day international fifty, was the centrepiece of South Africa's total of 173 for four.
The opener - batting in Smith's place - was appearing in only his second one-day international, four years after his debut against England at Lord's.
"He showed the selectors what he can do and it's fantastic he's taken the opportunity," said Kallis of van Wyk.
Fast bowler Andre Nel, all-rounder Andrew Hall and seamer Charl Langeveldt, all of whom have appeared in English county cricket this season, didn't play Sunday but are in Ireland as members of a 14-man squad.
"We will have some new faces out against India," said Kallis.
"Being rusty will be against us. India have played a lot of cricket and we aren't as well prepared as we want to be.
"But I think conditions might play into our hands with the ball seaming around a bit. Having said that they have world-class players who can produce big innings."