Chanderpaul, who averaged over 148 during England's 3-0 Test series win, showed his ability as a one-day batsman by scoring 116 not out in West Indies' 61-run victory in the second one-day international at Edgbaston on Wednesday.
However, during the course of his innings, the 32-year-old strained ligaments in his right ankle and was unable to field.
"They (the medical staff) have worked very hard on his injury over the last couple of days and he's having a hit in the nets today," Moore told reporters at England's National Cricket Performance Centre here Friday, where both teams trained indoors after rain prevented outdoor practice at Trent Bridge.
"We are very hopeful he will be right for tomorrow (Saturday)," the Australian added. "The physio has been working on him constantly.
"It's been very advantageous for us to have Shivvy playing in the role he's played," Moore said of the experienced left-hander, promoted to No 3 from No 5 at Edgbaston after his unbeaten 53 in West Indies' 79-run defeat in Sunday's series opener at Lord's.
"He's very versatile. He's played exceptionally well in the Test matches and now in the Twenty20s and one-dayers he's been fantastic.
"It just shows the quality of the player. When a man like that can do what he's done, it's no fluke.
"We know he works very hard at his game and he's a true professional.
He added Chanderpaul, who batted for over 24 hours in the Test series, had been an inspiration to all his team-mates.
"The good thing about Chanderpaul is he's always available to talk to players, he never cuts himself off.
"You don't even have to talk to Chanderpaul, you just stick your head out that window there and see how he trains and you'll see why he scores runs.
"He's obviously got a level of skill but he works very hard at his game."
West Indies, who like England failed to reach the World Cup semi-finals in the Caribbean, have gone 20 Tests without a win and Moore said a series success outside the Caribbean would be a cherished achievement.
"It would be nice to win something away from home. As I've been saying from day one of this tour, it's all about consistency and we have let ourselves down badly in our inconsistency.
"If we could put two good games together it would be very good but, in the big picture, it would still only be two games."
Moore, who replaced fellow Australian Bennett King after the World Cup, is set to continue coaching the West Indies during September's World Twenty20 in South Africa. But after that his future is uncertain.
"The arrangement was, unless they found someone, I would continue on for the Twenty20 but I'm not really concerned about where I'm going at the moment," Moore said.