Andrew Flintoff was ruled out of the fifth one-day international against India at Headingley here Sunday after suffering an injury to his troublesome left ankle.
An England and Wales Cricket Board (ECB) statement issued Sunday, said: "Andrew Flintoff is receiving specialist assessment on his left ankle and will rejoin the England squad on Tuesday prior to the next ODI at the Brit Oval (on Wednesday).
All-rounder Flintoff didn't bowl in the nets at Yorkshire's headquarters on Saturday, although he did bat.
He felt some soreness in his ankle after the team's three-wicket win against India at the player's Old Trafford home ground on Thursday.
The 29-year-old, a fast bowler and middle-order batsman, has had three operations on his left ankle during the past three seasons.
Flintoff hadn't played any international cricket at all this season until returning for the start of the ongoing seven match one-day series with India.
In the second match of the series, at Bristol a week last Friday, he took career-best figures of five for 56.
However, he missed the third match of the campaign, at Edgbaston, with a right knee injury.
England captain Paul Collingwood indicated Saturday that fast bowler Chris Tremlett was in line to replace Flintoff, however seamer Jon Lewis has finally replaced Flintoff after Tremlett was ruled out with soreness in his right foot.
India made one change, playing an extra batsman in Gautam Gambhir with left-arm quick Rudra Pratap Singh dropped.
England are 3-1 up in the series and a win at Headingley will give them an unbeatable lead ahead of next week's matches in London at The Oval and Lord's.