Ganga will partner Devon Smith at the top order when play starts at 1030am (4:30 am Eastern Caribbean Time).
The team will be captained by Dwayne Bravo, who continues to stand-in for Chris Gayle, still recovering from a hamstring injury sustained on the tour of Zimbabwe.
The West Indies will use the match as part of their continued preparation for the first Test against South Africa at Sahara Oval in Port Elizabeth, starting on December 26.
West Indies: Dwayne Bravo (captain), Devon Smith, Daren Ganga, Runako Morton, Shiv Chanderpaul, Marlon Samuels, Denesh Ramdin, Rawl Lewis, Darren Sammy, Pedro Collins, Fidel Edwards.
Reserves: Brenton Parchment, Jerome Taylor, Daren Powell.