The Bermuda side was hopelessly out of its depth and took 18 overs to reach their total of 13, only for it to be passed inside one over of the South African innings.
Right-arm spinner Sunette Loubser was the pick of the South African bowlers, taking 6 for 3 from four overs.
Alicia Smith finished with figures of 2 for 1 and Susan Benade 2 for 3.
Terry-Lynn Paynter opened the bowling for Bermuda, but conceded nine wides and a no-ball.
However this feat will not enter the record books as Bermuda is ranked outside the top ten countries.
Bermuda captain Linda Mienzer tried to take positives from the game.
"I am extremely proud and our team is very proud to be here," she said. "Just a year and a half ago there was no women's programme so we went to Canada and qualified to come here which is an achievement in itself."
"In terms of women's cricket in Bermuda, it has come a long way but we still have a long way to go."
Loubser warned her team-mates not to underestimate Tuesday's opponents, Papua New Guinea, before they complete the round-robin phase against Holland on Thursday.
"We don't know anything about our next opponents, but that doesn't mean we should rest on our laurels. We should be ready for anything."
In the other ties, Pakistan beat Ireland by 57 runs. Pakistan made 165/9 in 50 overs. In reply, Ireland could muster only 108 all out, Cecilia Joyce top-scoring with 36.
Zimbabwe overpowered Scotland by 75 runs against Zimbabwe.
The top two teams of the eight in the fray will make it to the Women's World Cup slated next year in Australia.