If they manage to win here, it will be the first time that India would have won three successive Tests against Australia in a series.
India won convincingly in Chennai and Hyderabad. Now the action shifts to the northern part of the country and India's domination could continue with the visitors' plans upset by off-field controversies.
Australia have only 13 players to choose their 11 for this Test. They have axed four players - Shane Watson, James Pattinson, Usman Khawaja and Mitchell Johnson for disciplinary reasons.
Already reeling under two successive losses, Australia have lot of problems to deal with, apart from tackling Indian spinners. Watson has left the tour after being axed and is not sure whether he will be back for the fourth and final Test in Delhi.
Last year, India were whitewashed 0-4 by Australia Down Under. MS Dhoni and his men have a great chance to inflict the same humiliation on them now. Never have India won 4-0 over Australia.
India's best wins over Australia have been by 2-0 margin on three occasions, 1979-80 (six-Test series), 2008-09 (four Tests) and 2010-11 (two Tests).
Barring the omission of Virender Sehwag from the squad of 15, India have retained the same 14 who did duty in the first two Tests. Though it is unlikely that India will change the winning combination, there is talk that Pragyan Ojha might come in for Harbhajan Singh, who has not been at his best.
Shikhar Dhawan is confirmed to make his Test debut and will open the batting with Murali Vijay.
Cheteshwar Pujara, who took a blow on his left knee on Tuesday, is declared fit to take the field tomorrow.
India are looking good with R Ashwin have shone with the ball and also their batters have been in form.
For Australia, Brad Haddin has joined the squad as cover for the injured Matthew Wade. There was still doubt over Wade's fitness and Haddin is expected to take over gloves behind the stumps.
Australia have lost both their Tests against India in Mohali. In 2008, they were thrashed by 320 runs while in 2010, VVS Laxman's heroics won the game by one wicket. India are unbeaten for 16 years in Mohali.
It is advantage India again and the pitch is expected to assist spinners.
India: MS Dhoni (captain), Murali Vijay, Shikhar Dhawan, Cheteshwar Pujara, Sachin Tendulkar, Virat Kohli, Ajinkya Rahane, Ravindra Jadeja, R Ashwin, Harbhajan Singh, Pragyan Ojha, Ishant Sharma, Ashok Dinda, Bhuvneshwar Kumar.
Australia: Michael Clarke (captain), Ed Cowan, David Warner, Phil Hughes, Matthew Wade, Glenn Maxwell, Peter Siddle, Mitchell Starc, Nathan Lyon, Moises Henriques, Xavier Doherty, Steve Smith, Brad Haddin.
Match starts at 9.30 AM IST
First Test: India won by eight wickets
Second Test: India won by innings and 135 runs